Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22727981 | 0.90 | HDAC3 (0.52) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL27797896 | 0.84 | HDAC3 (0.52) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31644307 | 0.84 | HDAC3 (0.52) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL13975444 | 0.84 | LMNA (0.47) | JAK3BTKTDP1STK17BSTK17A | |
| SCHEMBL28375889 | 0.83 | HDAC8 (0.53) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31319590 | 0.83 | HDAC3 (0.51) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL24613337 | 0.83 | KMT2A (0.43) | HDAC3HDAC8NCOR2JAK3BTK | |
| SCHEMBL16899828 | 0.83 | ALDH1A1 (0.41) | JAK3BTKTDP1STK17BSTK17A | |
| SCHEMBL13740008 | 0.83 | ALDH1A1 (0.41) | JAK3BTKTDP1STK17BSTK17A | |
| SCHEMBL19558618 | 0.83 | ALDH1A1 (0.41) | JAK3BTKTDP1STK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110366549-A | Compound as interleukin-1 activity inhibitor | 基因泰克公司 | 2019-10-22 | — | — | CN | disclosed |