Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319590 | 0.85 | HDAC3 (0.51) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL27797896 | 0.84 | HDAC3 (0.52) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL31319580 | 0.83 | AR (0.56) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL31319666 | 0.82 | HDAC3 (0.48) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL31319588 | 0.80 | AR (0.56) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL22727981 | 0.79 | HDAC3 (0.52) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL28321163 | 0.79 | HDAC3 (0.52) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL31644307 | 0.79 | HDAC3 (0.52) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL31319639 | 0.79 | HDAC3 (0.49) | ARHDAC3HDAC8NCOR2SCD | |
| SCHEMBL28375889 | 0.78 | HDAC8 (0.53) | ARHDAC3HDAC8NCOR2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |