Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL22721144 | 0.89 | BPTF (0.41) | BPTFHTR1ADRD2HTR2ASLC6A2 | |
| SCHEMBL22728587 | 0.88 | BPTF (0.47) | BPTFHTR1ASLC6A2SLC6A4SLC6A3 | |
| Maleic Acid SCHEMBL22721031 | 0.78 | SIGMAR1 (0.43) | BPTFCHRNB2CHRNA4CHRNA7 | |
| SCHEMBL22728605 | 0.75 | BPTF (0.44) | BPTFCHRNB2CHRNA4CHRNA7KHK | |
| SCHEMBL29732528 | 0.75 | BPTF (0.44) | BPTFCHRNB2CHRNA4CHRNA7KHK | |
| Hydrochloric Acid SCHEMBL29732532 | 0.74 | BPTF (0.43) | BPTFCHRNB2CHRNA4CHRNA7KHK | |
| Hydrochloric Acid SCHEMBL22721131 | 0.74 | BPTF (0.43) | BPTFCHRNB2CHRNA4CHRNA7KHK | |
| SCHEMBL22721059 | 0.74 | BPTF (0.62) | BPTFCHRNB2CHRNA4CHRNA7KHK | |
| SCHEMBL29604990 | 0.74 | TERT (0.50) | HTR1ADRD2HTR2ASLC6A2SLC6A4 | |
| SCHEMBL22728519 | 0.74 | SLC6A2 (0.42) | HTR1ADRD2HTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239073-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-03 | — | — | WO | disclosed |