Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15596306 | 0.84 | GPR119 (0.67) | PDE10AGPR119OPRM1OPRD1OPRK1 | |
| SCHEMBL10111733 | 0.84 | GPR119 (0.67) | PDE10AGPR119OPRM1OPRD1OPRK1 | |
| SCHEMBL928382 | 0.82 | GPR119 (0.53) | PDE10AGPR119NR1H2 | |
| SCHEMBL652572 | 0.82 | PDE10A (0.54) | PDE10AGPR119OPRM1OPRD1OPRK1 | |
| SCHEMBL652571 | 0.82 | PDE10A (0.54) | PDE10AGPR119OPRM1OPRD1OPRK1 | |
| SCHEMBL3541614 | 0.81 | JAK1 (0.47) | GPR119NR1H2KCNK3KCNK9 | |
| SCHEMBL25591596 | 0.81 | MAPT (0.50) | GPR119LIPENR1H2 | |
| SCHEMBL20511423 | 0.81 | GPR119 (0.70) | PDE10AGPR119NR1H2 | |
| SCHEMBL20511395 | 0.81 | ALDH1A1 (0.52) | GPR119LIPENR1H2 | |
| SCHEMBL20511076 | 0.80 | GPR119 (0.67) | PDE10AGPR119LIPENR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239073-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-03 | — | — | WO | disclosed |