SCHEMBL2272885

SCHEMBL2272885

CCC[Si](c1ccccc1)(c1ccccc1)N(C)C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
TP53 P04637 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
AOC3 Q16853 2/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KCNA5 P22460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273997 0.81 MAPT (0.33) ALDH1A1TSHRTP53KDM4EGAA
SCHEMBL2102725 0.78 ALDH1A1 (0.33) ALDH1A1TSHRTP53SIGMAR1KDM4E
SCHEMBL28218923 0.77 TP53 (0.38) ALDH1A1TSHRTP53SIGMAR1KDM4E
SCHEMBL2272365 0.75 ALDH1A1 (0.31) ALDH1A1TSHRTP53SIGMAR1
SCHEMBL2102658 0.75 ALDH1A1 (0.31) ALDH1A1TSHRTP53SIGMAR1
SCHEMBL2100450 0.72 ALDH1A1 (0.32) ALDH1A1KDM4EGAAHPGD
SCHEMBL2275317 0.72 AOC3 (0.32) SIGMAR1AOC3HTR2AHRH1TDP1
SCHEMBL2101652 0.72
SCHEMBL3889886 0.72 NR1H2 (0.50) ALDH1A1TSHRTP53KDM4EGAA
SCHEMBL10730048 0.72 ESR1 (0.45) ALDH1A1TSHRTP53KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed