Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729264 | 1.00 | TAS1R3 (0.40) | TAS1R3TAS1R1TSHRALDH1A1PTPN1 | |
| SCHEMBL1686949 | 0.96 | — | — | |
| SCHEMBL1686947 | 0.96 | — | — | |
| SCHEMBL2128303 | 0.86 | TAS1R3 (0.48) | TAS1R3TAS1R1ALDH1A1PTPN1PPARA | |
| SCHEMBL9069564 | 0.86 | TAS1R3 (0.48) | TAS1R3TAS1R1ALDH1A1PTPN1PPARA | |
| SCHEMBL647051 | 0.84 | TOP1 (0.50) | TSHRPPARA | |
| SCHEMBL647052 | 0.84 | TOP1 (0.50) | TSHRPPARA | |
| SCHEMBL17294082 | 0.83 | TSHR (0.48) | TSHRALDH1A1PTPN1PPARAHPGD | |
| SCHEMBL17294081 | 0.83 | TSHR (0.48) | TSHRALDH1A1PTPN1PPARAHPGD | |
| SCHEMBL5925126 | 0.81 | PPARG (0.49) | TSHRPTPN1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649220-B2 | Probucol derivative, preparation method therefor and use thereof | DEMOTECH.INC. (CN) | 2023-05-16 | — | — | US | disclosed |
| US-20210040052-A1 | PROBUCOL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | DEMOTECH.INC. (CN) | 2021-02-11 | — | — | US | disclosed |
| EP-3747863-A1 | PROBUCOL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | DEMOTECH.INC. (CN) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040052-A1 | PROBUCOL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | PNLIP, FAR1, CETP | TAS1R3 2712/4885TAS1R1 2403/4885TSHR 3501/4885 |
| US-11649220-B2 | Probucol derivative, preparation method therefor and use thereof | PNLIP, FAR1, CETP | TAS1R3 2712/4885TAS1R1 2403/4885TSHR 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.