Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.37 |
| ▸ | MET | P08581 | 7/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729926 | 0.89 | MET (0.36) | ADORA2AADORA1METADORA3 | |
| SCHEMBL15288815 | 0.89 | MET (0.45) | MET | |
| Hydrochloric Acid SCHEMBL15288453 | 0.88 | MET (0.44) | MET | |
| SCHEMBL15288305 | 0.88 | MET (0.45) | MET | |
| SCHEMBL20530304 | 0.87 | ADORA2A (0.38) | ADORA2AADORA1METDGAT2 | |
| SCHEMBL22729929 | 0.85 | HDAC6 (0.39) | ADORA2AADORA1ADORA3 | |
| SCHEMBL22729921 | 0.84 | ADORA2A (0.38) | ADORA2AADORA1MET | |
| SCHEMBL22729930 | 0.81 | MET (0.36) | MET | |
| SCHEMBL15288378 | 0.80 | MET (0.48) | MET | |
| Hydrochloric Acid SCHEMBL15288738 | 0.79 | MET (0.47) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2831073-B1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN KINASES | RHIZEN PHARMACEUTICALS S A (CH) | 2020-12-09 | — | — | EP | claimed |