Sugi Predict

Sugi Predict / Compounds / SCHEMBL22730895

SCHEMBL22730895

SCHEMBL22730895

O=C1c2cc(F)ncc2-c2cc3cccccc-3c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPRC P08575 2/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ ADORA2A P29274 3/20 0.38
▸ ADORA1 P30542 3/20 0.38
▸ NPC1 O15118 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ APAF1 O14727 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ XBP1 P17861 1/20 0.37
▸ PTBP1 P26599 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ GALK1 P51570 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ SMAD3 P84022 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22730645 0.76 PTPRC (0.51) PTPRCPTPN1ADORA2AADORA1NPC1
SCHEMBL22730681 0.76 ADORA2A (0.34) PTPRCPTPN1ADORA2AADORA1NPC1
SCHEMBL22730653 0.76 MAPT (0.59) PTPRCPTPN1ADORA2AADORA1NPC1
SCHEMBL22730634 0.75 MAOB (0.58) ADORA2AADORA1NPC1MAPTRAB9A
SCHEMBL22730906 0.73 ALDH1A1 (0.38) ADORA2AADORA1NPC1MAPTRAB9A
SCHEMBL22730649 0.73 MAPT (0.51) PTPRCPTPN1ADORA2AADORA1NPC1
SCHEMBL25620878 0.72 HPGD (0.36) ADORA2AADORA1HTTKCNH2
SCHEMBL22730644 0.71 PTPRC (0.49) PTPRCPTPN1ADORA2AADORA1NPC1
SCHEMBL22730640 0.71 PTPRC (0.49) PTPRCPTPN1ADORA2AADORA1NPC1
SCHEMBL25620943 0.70 ELANE (0.59) PTPRCPTPN1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-06 — — US disclosed
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-06 — — US disclosed
US-20200377467-A1 Azulene ring-containing compound, its use, and an organic photoelectric device including the same Shanghai Tianma AM-OLED Co., Ltd., Shanghai, CHINA 2020-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same CCNE2, CCNE1, ESR1 PTPRC 1747/4885PTPN1 2430/4885ADORA2A 1213/4885
US-20200377467-A1 Azulene ring-containing compound, its use, and an organic photoelectric device including the same CCNE2, CCNE1, ESR1 PTPRC 1747/4885PTPN1 2430/4885ADORA2A 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.