SCHEMBL22730653

SCHEMBL22730653

O=C1c2ccccc2-c2cc3cccccc-3c21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.59
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
LMNA P02545 3/20 0.59
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
APAF1 O14727 2/20 0.59
THRB P10828 2/20 0.59
HTT P42858 2/20 0.59
GALK1 P51570 2/20 0.59
BLM P54132 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
XBP1 P17861 1/20 0.59
PTBP1 P26599 1/20 0.59
SMAD3 P84022 1/20 0.59
ATM Q13315 1/20 0.59
PTPRC P08575 4/20 0.50
MAOA P21397 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL978115 0.88 MAPT (0.60) MAPTMEN1KMT2ALMNANPC1
SCHEMBL19001705 0.86 MAPT (0.58) MAPTMEN1KMT2ALMNANPC1
SCHEMBL978805 0.84 MAPT (0.57) MAPTMEN1KMT2ALMNANPC1
SCHEMBL22730649 0.84 MAPT (0.51) MAPTMEN1KMT2ALMNANPC1
SCHEMBL25620958 0.84 ELANE (0.59) MAPTMEN1KMT2ALMNANPC1
SCHEMBL22730645 0.84 PTPRC (0.51) MAPTMEN1KMT2ALMNANPC1
SCHEMBL25620943 0.84 ELANE (0.59) MAPTMEN1KMT2ALMNANPC1
SCHEMBL22730634 0.82 MAOB (0.58) MAPTMEN1KMT2ALMNANPC1
SCHEMBL10481647 0.81 LMNA (0.45) MAPTMEN1KMT2ALMNANPC1
SCHEMBL22182158 0.80 TDP2 (0.51) MAPTMEN1KMT2ALMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-06 US disclosed
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-06 US disclosed
US-20200377467-A1 Azulene ring-containing compound, its use, and an organic photoelectric device including the same Shanghai Tianma AM-OLED Co., Ltd., Shanghai, CHINA 2020-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same CCNE2, CCNE1, ESR1 MAPT 1535/4885MEN1 959/4885KMT2A 1591/4885
US-20200377467-A1 Azulene ring-containing compound, its use, and an organic photoelectric device including the same CCNE2, CCNE1, ESR1 MAPT 1535/4885MEN1 959/4885KMT2A 1591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.