Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.93 |
| ▸ | DAO | P14920 | 1/20 | 0.93 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.93 |
| ▸ | CES2 | O00748 | 3/20 | 0.74 |
| ▸ | CES1 | P23141 | 3/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11785386 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3966600 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL137419 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11602198 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7719037 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL976149 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL407365 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL149318 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL975929 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1378 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11472897-B2 | Methods of preparing a catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2022-10-18 | — | — | US | claimed |
| US-20220056173-A1 | Methods of Preparing a Catalyst | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2022-02-24 | — | — | US | claimed |
| US-11125688-B2 | Use of turbidimeter for measurement of solid catalyst system component in a reactor feed | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2021-09-21 | — | — | US | claimed |
| US-20200319103-A1 | Use of Turbidimeter for Measurement of Solid Catalyst System Component in a Reactor Feed | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2020-10-08 | — | — | US | claimed |
| CN-106927988-B | Preparation method of decene | 中国石油天然气股份有限公司 | 2019-12-06 | — | — | CN | claimed |
| CN-109747227-A | A kind of resin plate and preparation method for silicon wafer cutting | 苏州柯莱美高分子材料科技有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-104163906-B | One kind is used for isocyanate trimerization, catalyst and its application of the isocyanates with epoxy annulation | 华东理工大学 | 2018-01-05 | — | — | CN | claimed |
| CN-106927988-A | Preparation method of decene | 中国石油天然气股份有限公司 | 2017-07-07 | — | — | CN | claimed |
| CN-103464204-B | The method preparing olefin oligomerization catalyst | 切夫里昂菲利普化学有限责任公司 | 2016-08-10 | — | — | CN | claimed |
| CN-103483718-B | Ventilative artificial PVC leather with microvoid structure and preparation method thereof | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-01-06 | — | — | CN | claimed |
| EP-0962471-B1 | Catalyst composition and polymerization process for producing syndiotactic 1,2-polybutadiene | BRIDGESTONE CORP (JP) | 2003-07-16 | — | — | EP | claimed |
| EP-0926167-B1 | Preparation of syndiotactic 1,2-polybutadiene using a chromium-containing catalyst system | BRIDGESTONE CORP (JP) | 2002-11-06 | — | — | EP | claimed |
| US-6201080-B1 | CATALYTIC POLYMERIZATION OF BUTADIENE IN A SOLVENT | BRIDGESTONE CORPORATION (JP) | 2001-03-13 | — | — | US | claimed |
| US-6117956-A | COORDINATION CATALYST CONTAINING CHROMIUM COMPOUND, ORGANOMAGNESIUM COMPOUND AND A PHOSPHITE | BRIDGESTONE CORPORATION (JP) | 2000-09-12 | — | — | US | claimed |
| EP-0962471-A1 | Catalyst composition and polymerization process for producing syndiotactic 1,2-polybutadiene | Bridgestone Corporation (JP) | 1999-12-08 | — | — | EP | claimed |
| EP-0926167-A1 | Preparation of syndiotactic 1,2-polybutadiene using a chromium-containing catalyst system | Bridgestone Corporation (JP) | 1999-06-30 | — | — | EP | claimed |
| US-4337227-A | Recovery of chromium from waste solutions | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) | 1982-06-29 | — | — | US | claimed |
| US-4231967-A | REACTION OF A PHENOL AND FORMALDEHYDE USING AN ORGANIC CHROMIUM OR IRON COMPOUND AS CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-11-04 | — | — | US | claimed |
| US-4196098-A | CHROMIUM CARBOXYLATE, SUPPORT, ACTIVATION | CHEMPLEX COMPANY (US) | 1980-04-01 | — | — | US | claimed |
| US-4117217-A | CATALYST COMPRISING A SUPPORTED CHROMIUM DERIVATIVE OF A CARBOXYLIC ACID | CHEMPLEX COMPANY (US) | 1978-09-26 | — | — | US | claimed |