Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26937859 | 0.94 | REN (0.32) | REN | |
| SCHEMBL26327792 | 0.90 | — | — | |
| SCHEMBL22320759 | 0.85 | APP (0.35) | REN | |
| SCHEMBL26937855 | 0.85 | APP (0.35) | REN | |
| SCHEMBL22732795 | 0.83 | APP (0.33) | REN | |
| SCHEMBL17283042 | 0.80 | GAA (0.36) | — | |
| SCHEMBL18681186 | 0.78 | BCHE (0.35) | REN | |
| SCHEMBL26938494 | 0.78 | KLK7 (0.30) | — | |
| SCHEMBL23605182 | 0.78 | GAA (0.35) | — | |
| SCHEMBL22732797 | 0.78 | TUBB4A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289480-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2020243155-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | GENENTECH, INC. (US) | 2020-12-03 | — | — | WO | disclosed |