Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618591 | 0.95 | GPR119 (0.52) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL2657012 | 0.94 | HPGD (0.57) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| Dimethyl Sulfoxide SCHEMBL7366526 | 0.92 | HPGD (0.49) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL31270977 | 0.91 | HPGD (0.48) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL23826030 | 0.90 | HPGD (0.56) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL35456 | 0.90 | HPGD (0.49) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL35457 | 0.90 | HPGD (0.49) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL935410 | 0.90 | HPGD (0.49) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL30258404 | 0.88 | GPR119 (0.56) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL30776116 | 0.87 | HPGD (0.45) | HPGDRECQLEPHX1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4231 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004862-A | Compound, pharmaceutical composition and application thereof | 山东大学 | 2025-05-16 | — | — | CN | claimed |
| CN-117777098-A | 4-aminoindazole double-target inhibitor and preparation method and application thereof | 成都市第三人民医院 | 2024-03-29 | — | — | CN | claimed |
| CN-114605385-B | Indole piperidine urea TRPV1 antagonism/FAAH inhibition double-target drug, preparation method and application | 河南大学 | 2023-09-08 | — | — | CN | claimed |
| CN-114591327-B | Indoline piperidine urea TRPV1 antagonism and MOR agonism double-target-point medicine, preparation method and application | 河南大学 | 2023-02-07 | — | — | CN | claimed |
| CN-115124457-A | Synthetic method of 1-methyl-4- (4-piperidyl) piperazine hydrochloride | 浙江海昇药业股份有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-114591327-A | Indoline piperidine urea type TRPV1 antagonistic and MOR agonistic double-target-point medicine, preparation method and application | 河南大学 | 2022-06-07 | — | — | CN | claimed |
| CN-109535019-B | 1,1a,6,6 a-tetrahydrocyclopropa [ a ] indene-1-amine derivative and preparation method and application thereof | 华东师范大学 | 2021-08-20 | — | — | CN | claimed |
| CN-107652226-B | Preparation method of N-Boc-4-piperidine formaldehyde | 上海皓伯化工科技有限公司 | 2020-03-31 | — | — | CN | claimed |
| CN-106146459-B | Preparation method of bilastine | 山东罗欣药业集团恒欣药业有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-109535019-A | 1,1a, 6,6a- tetrahydro cyclopropyl simultaneously [a] indenes -1- amine derivative and the preparation method and application thereof | 华东师范大学 | 2019-03-29 | — | — | CN | claimed |
| US-20040116491-A1 | Triazolone and triazolethione derivatives as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme | BRISTOL-MYERS SQUIBB COMPANY | 2004-06-17 | — | — | US | claimed |
| WO-2004032846-A2 | TRIAZOLONE AND TRIAZOLETHIONE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-22 | — | — | WO | claimed |
| US-20040029880-A1 | Anthranyl amides and their use as medicaments | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | US | claimed |
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | claimed |
| US-20030092634-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2003-05-15 | — | — | US | claimed |
| US-6506733-B1 | Which process comprises hydrogenating a compound of Formula 9: presence of a catalytic amount of 20% palladium hydroxide on carbon. | AXYS PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | claimed |
| JP-2002539201-A | — | — | 2002-11-19 | — | — | JP | claimed |
| CN-1345314-A | Amine derivatives as protease inhibitors | AXYS PHARM INC (US) | 2002-04-17 | — | — | CN | claimed |
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |