Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21405091 | 0.90 | GPR119 (0.52) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL21405090 | 0.90 | GPR119 (0.52) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL2770208 | 0.89 | GPR119 (0.61) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL227336 | 0.88 | HPGD (0.55) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL14634495 | 0.83 | GPR119 (0.56) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL14634494 | 0.83 | GPR119 (0.56) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL27618591 | 0.83 | GPR119 (0.52) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL21456062 | 0.83 | HPGD (0.58) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL2657012 | 0.82 | HPGD (0.57) | GPR119HPGDRECQLEPHX1USP2 | |
| SCHEMBL31282437 | 0.82 | GPR119 (0.58) | GPR119HPGDRECQLEPHX1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059792-A1 | CORONAVIRUS NON-STRUCTURAL PROTEIN 3 DEGRADING COMPOUNDS | C4 THRAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |