SCHEMBL22733748

SCHEMBL22733748

C=C(C)C(=O)OC(C)(C)S

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 3/20 0.37
THRB P10828 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
HSD17B10 Q99714 1/20 0.31
DGAT1 O75907 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571060 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL8849501 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL33412 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL1498046 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTHRBTDP1HSD17B10
Ammonia Solution, Strong SCHEMBL1022660 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL865012 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL168270 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTHRBTDP1HSD17B10
Ethylene SCHEMBL16830236 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL22092440 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL29087105 0.76 ALDH1A1 (0.38) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3760656-B1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER POWDER, AND RESIN COMPOSITION USING THE SAME, AND MOLDED ARTICLE FORMED OF THE SAME MITSUBISHI CHEM CORP (JP) 2023-12-27 EP disclosed
CN-110869355-B Benzopyran compound, curable composition containing the compound, and optical article containing cured product formed from the curable composition 株式会社德山 2023-11-14 CN disclosed
CN-112424260-B Photochromic compound and curable composition containing the same 株式会社德山 2023-10-13 CN disclosed
CN-111788241-B Polyorganosiloxane-containing graft copolymer powder, resin composition using same, and molded article comprising same 三菱化学株式会社 2023-05-12 CN disclosed
US-11548968-B2 Polyorganosiloxane-containing graft copolymer powder, and resin composition using the same, and molded article formed of the same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-01-10 US disclosed
EP-3760656-A1 POWDER OF POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION INCLUDING SAME, AND MOLDED OBJECT OF SAID RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2021-01-06 EP disclosed
US-20200385504-A1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER POWDER, AND RESIN COMPOSITION USING THE SAME, AND MOLDED ARTICLE FORMED OF THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2020-12-10 US disclosed
CN-111788241-A Polyorganosiloxane-containing graft copolymer powder, resin composition using the same, and molded article made of the resin composition 三菱化学株式会社 2020-10-16 CN disclosed
CN-106999442-A Process for preparing drug-polymer compositions 基里特·帕特尔 2017-08-01 CN disclosed
CN-103298495-A Polymerizable composition for ophthalmic and medical use and antibacterial composition obtained by polymerizing same UNIV NANYANG TECH 2013-09-11 CN disclosed
CN-100529842-C Highly safe silicone-containing material for ocular lens and process for producing the same MENICON CO LTD (JP) 2009-08-19 CN disclosed
CN-1723411-A High-safety ophthalmic lens material containing silicone and method for producing same MENICON CO LTD (JP) 2006-01-18 CN disclosed