⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454166 | 0.76 | PNP (0.32) | — | |
| SCHEMBL17556623 | 0.71 | NOS1 (0.49) | — | |
| SCHEMBL7359692 | 0.67 | NOS1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL16741182 | 0.67 | KDM4E (0.36) | — | |
| SCHEMBL7077081 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL7362056 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL2044798 | 0.65 | NOS1 (0.49) | — | |
| SCHEMBL3454198 | 0.64 | CYP3A4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL28835504 | 0.63 | KDM4E (0.33) | — | |
| SCHEMBL851106 | 0.62 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| WO-2011138142-A1 | COMPOSITIONS AND USE OF SULFASALAZINE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2011-11-10 | — | — | WO | claimed |
| US-20110207753-A1 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2011-08-25 | — | — | US | claimed |
| EP-1696877-A2 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2006-09-06 | — | — | EP | claimed |
| US-20050197341-A1 | Methods for treating pain | GENERAL HOSPITAL CORPORATION, THE | 2005-09-08 | — | — | US | claimed |
| WO-2005048926-A2 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2005-06-02 | — | — | WO | claimed |
| EP-0012444-A1 | Diagnostic method, especially for the early recognition of malignant tumors and/or viral diseases, and means to carry it out | Wachter, Helmut, Univ.-Prof. Dr. (AT) | 1980-06-25 | — | — | EP | claimed |
| US-20260124144-A1 | COMPOSITIONS COMPRISING DISODIUM LEVOFOLINATE | Acrotech Biopharma Inc. (US) | 2026-05-07 | — | — | US | disclosed |
| US-12564556-B1 | Compositions comprising disodium levofolinate | Acrotech Biopharma Inc. (US) | 2026-03-03 | — | — | US | disclosed |
| US-12539276-B1 | Compositions comprising disodium levofolinate | Acrotech Biopharma Inc. (US) | 2026-02-03 | — | — | US | disclosed |
| US-11541012-B1 | Compositions comprising disodium levofolinate | Acrotech Biopharma, LLC (US) | 2023-01-03 | — | — | US | disclosed |
| CN-105229002-A | BET protein inhibiting dihydropyridopyrazinones | Bayer Pharma AG | 2016-01-06 | — | — | CN | disclosed |
| WO-2011138142-A1 | COMPOSITIONS AND USE OF SULFASALAZINE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2011-11-10 | — | — | WO | disclosed |
| EP-0012444-B1 | DIAGNOSTIC METHOD, ESPECIALLY FOR THE EARLY RECOGNITION OF MALIGNANT TUMORS AND/OR VIRAL DISEASES, AND MEANS TO CARRY IT OUT | Wachter, Helmut, Univ.-Prof. Dr. (AT) | 1984-07-25 | — | — | EP | disclosed |
| EP-0012444-A1 | Diagnostic method, especially for the early recognition of malignant tumors and/or viral diseases, and means to carry it out | Wachter, Helmut, Univ.-Prof. Dr. (AT) | 1980-06-25 | — | — | EP | disclosed |