Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261845 | 0.86 | TSHR (0.64) | TSHRMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL22734285 | 0.84 | ANO1 (0.54) | MAPTKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL22734280 | 0.83 | NPC1 (0.49) | ALDH1A1 | |
| SCHEMBL23327862 | 0.77 | BRD4 (0.68) | TSHRMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10340271 | 0.76 | KDM4E (0.77) | TSHRMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL34463090 | 0.75 | TSHR (0.55) | TSHRMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8049389 | 0.74 | MEN1 (0.76) | TSHRMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31393812 | 0.74 | MEN1 (0.76) | TSHRMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31240678 | 0.71 | GAA (0.62) | TSHRMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28000025 | 0.71 | HSD17B13 (0.55) | TSHRMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200383988-A1 | Compounds | ENTERPRISE THERAPEUTICS HOLDINGS LIMITED (GB) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200383988-A1 | Compounds | CACNA1E, TMEM109, CACNA1A | TSHR 2117/4885MAPT 4004/4885KDM4E 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.