Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TXN | P10599 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073559 | 0.80 | NPSR1 (0.58) | NPSR1DDAH1KDM4ETXNCYP1A2 | |
| SCHEMBL22016725 | 0.79 | NPSR1 (0.56) | NPSR1DDAH1KDM4ETXNCYP1A2 | |
| SCHEMBL22926257 | 0.78 | NPSR1 (0.54) | NPSR1DDAH1KDM4ETXNCYP1A2 | |
| SCHEMBL229852 | 0.77 | NPSR1 (0.68) | NPSR1DDAH1KDM4ETXNCYP1A2 | |
| SCHEMBL20476291 | 0.76 | NPSR1 (0.53) | NPSR1DDAH1KDM4ETXNCYP1A2 | |
| SCHEMBL846351 | 0.76 | NPSR1 (0.66) | NPSR1DDAH1KDM4ETXNALDH1A1 | |
| SCHEMBL30633367 | 0.76 | NPSR1 (0.66) | NPSR1DDAH1KDM4ETXNALDH1A1 | |
| SCHEMBL14361622 | 0.75 | NPSR1 (0.51) | NPSR1DDAH1KDM4ETXNCYP1A2 | |
| SCHEMBL22017033 | 0.74 | NPSR1 (0.50) | NPSR1DDAH1KDM4ETXNCYP1A2 | |
| SCHEMBL20283848 | 0.73 | NPSR1 (0.58) | NPSR1DDAH1KDM4ETXNCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130750-B2 | Calcium channel inhibitors | CAVION, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-11130750-B2 | Calcium channel inhibitors | CAVION, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CAVION, INC. | 2020-12-10 | — | — | US | disclosed |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CAVION, INC. | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130750-B2 | Calcium channel inhibitors | CACNA1F, ORAI1, CACNA1E | NPSR1 2663/4885DDAH1 2205/4885KDM4E 528/4885 |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CACNA1F, ORAI1, CACNA1E | NPSR1 2663/4885DDAH1 2205/4885KDM4E 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.