Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187270 | 0.79 | GCGR (0.50) | CYP1A2CYP2C9KDM4ERAB9ANPC1 | |
| SCHEMBL12531367 | 0.79 | ERCC1 (0.46) | CYP1A2RAB9ANPC1CYP2C19SMN1; SMN2 | |
| SCHEMBL5503791 | 0.79 | CYP1A2 (0.56) | CYP1A2CYP2C9HSD17B10HTR6CTSV | |
| SCHEMBL28170953 | 0.78 | CYP1A2 (0.59) | CYP1A2CYP2C9HSD17B10NOTUMKDM4E | |
| SCHEMBL23303471 | 0.78 | CYP1A2 (0.50) | CYP1A2CYP2C9HSD17B10NOTUMKDM4E | |
| SCHEMBL22734803 | 0.78 | CYP1A2 (0.50) | CYP1A2CYP2C9HSD17B10NOTUMKDM4E | |
| SCHEMBL4491047 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2C9HSD17B10NOTUMKDM4E | |
| SCHEMBL1536003 | 0.75 | NOTUM (0.56) | CYP1A2CYP2C9HSD17B10NOTUMKDM4E | |
| SCHEMBL7106433 | 0.75 | CYP1A2 (0.61) | CYP1A2CYP2C9HSD17B10NOTUMKDM4E | |
| SCHEMBL17859651 | 0.74 | KDM4E (0.53) | CYP1A2CYP2C9HSD17B10TP53NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200384451-A1 | PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-12-10 | — | — | US | claimed |
| US-12024732-B2 | Method for preparing nitrogen-containing heterocyclic compound and derivative thereof by enzymatic-chemical cascade method | NANJING TECH UNIVERSITY (CN) | 2024-07-02 | — | — | US | disclosed |
| US-12024732-B2 | Method for preparing nitrogen-containing heterocyclic compound and derivative thereof by enzymatic-chemical cascade method | NANJING TECH UNIVERSITY (CN) | 2024-07-02 | — | — | US | disclosed |
| US-20240026400-A1 | METHOD FOR PREPARING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF BY ENZYMATIC-CHEMICAL CASCADE METHOD | NANJING TECH UNIVERSITY (CN) | 2024-01-25 | — | — | US | disclosed |
| US-20240026400-A1 | METHOD FOR PREPARING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF BY ENZYMATIC-CHEMICAL CASCADE METHOD | NANJING TECH UNIVERSITY (CN) | 2024-01-25 | — | — | US | disclosed |
| WO-2022110916-A1 | METHOD FOR PREPARING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF BY MEANS OF ENZYMATIC-CHEMICAL CASCADE METHOD | 南京工业大学 | 2022-06-02 | — | — | WO | disclosed |
| CN-112375040-B | Method for preparing nitrogen-containing heterocyclic compound and derivative thereof by enzyme-chemical cascade method | 南京工业大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-112375040-A | Method for preparing nitrogen-containing heterocyclic compound and derivative thereof by enzyme-chemical cascade method | 南京工业大学 | 2021-02-19 | — | — | CN | disclosed |
| US-20200384451-A1 | PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200384451-A1 | PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF | CPNE4, PPOX, PDCD5 | CYP1A2 353/4885CYP2C9 630/4885HSD17B10 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.