8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL22734876

Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.[AlH3]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.96
PLAU P00749 1/20 0.57
NCF1 P14598 1/20 0.57
RAB9A P51151 4/20 0.56
CCR1 P32246 1/20 0.56
CCR5 P51681 1/20 0.56
ALDH1A1 P00352 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55
HPGD P15428 1/20 0.55
ALOX12 P18054 1/20 0.55
CYP2C19 P33261 1/20 0.55
HIF1A Q16665 1/20 0.55
HSD17B10 Q99714 1/20 0.55
PARP1 P09874 1/20 0.53
KMT2A Q03164 6/20 0.52
KDM4E B2RXH2 5/20 0.52
SOS2 Q07890 1/20 0.52
MMP2 P08253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL28100096 1.00 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL29483489 0.98 METAP2 (1.00) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL297247 0.98 METAP2 (1.00) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL9154369 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL5089361 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL4762935 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL4304584 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL4286984 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL7179747 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1
8-Hydroxy Quinaldine SCHEMBL9154936 0.96 METAP2 (0.96) METAP2PLAUNCF1RAB9ACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200388791-A1 ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING CAPPING LAYER AND USE VALIANT CO., LTD. 2020-12-10 US disclosed