Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.96 |
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | CCR1 | P32246 | 1/20 | 0.56 |
| ▸ | CCR5 | P51681 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Hydroxy Quinaldine SCHEMBL297247 | 0.98 | METAP2 (1.00) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL29483489 | 0.98 | METAP2 (1.00) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL4762935 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL7179747 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL546577 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL9154369 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL9154936 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL5089361 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL22734876 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 | |
| 8-Hydroxy Quinaldine SCHEMBL4286984 | 0.96 | METAP2 (0.96) | METAP2PLAUNCF1RAB9ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516577-A | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| EP-0569827-A2 | Organic electroluminescence device | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | claimed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20070248769-A1 | Cover film for organic electroluminescence devices, organic electroluminescence device using the cover film and process for producing the device | TIS INTERNATIONAL, INC. | 2007-10-25 | — | — | US | disclosed |
| US-20070018568-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060228577-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2006-10-12 | — | — | US | disclosed |
| US-7008883-B2 | Photoresist composition for forming an insulation film, insulation film for organic electroluminescence devices and process for producing the insulation film | ZEON CORPORATION (JP) | 2006-03-07 | — | — | US | disclosed |
| US-20050275341-A1 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1599074-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-1560469-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-20050019585-A1 | comprises polymers of decomposition products of a perfluoroolefin (Perfluorocyclopentene); good transparency | ZEON CORPORATION (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1473974-A1 | COVER FILM FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME, AND ITS MANUFACTURING METHOD | ZEON CORPORATION (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-20040096771-A1 | Photoresist composition for forming an insulation film, insulation film for organic electroluminescence element and method for itis formation | ZEON CORPORATION (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1144543-B1 | ELECTROLUMINESCENT QUINOLATES | SOUTH BANK UNIV ENTPR LTD (GB) | 2004-03-17 | — | — | EP | disclosed |
| EP-1321821-A1 | PHOTORESIST COMPOSITION FOR FORMING INSULATION FILM, INSULATION FILM FOR ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR ITS FORMATION | NIPPON ZEON CO., LTD. (JP) | 2003-06-25 | — | — | EP | disclosed |
| EP-0781075-B1 | METHOD FOR SEALING ORGANIC EL ELEMENT AND ORGANIC EL ELEMENT | IDEMITSU KOSAN CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5962962-A | Method of encapsulating organic electroluminescence device and organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0781075-A1 | METHOD FOR SEALING ORGANIC EL ELEMENT AND ORGANIC EL ELEMENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5516577-A | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| EP-0569827-A2 | Organic electroluminescence device | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050275341-A1 | Coumarin compound | XPO1, VKORC1, XPO5 | METAP2 2661/4885PLAU 1222/4885NCF1 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.