Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220291 | 0.85 | ENPP2 (0.36) | ENPP2METCTSVCTSLCTSS | |
| SCHEMBL13275655 | 0.85 | PPARG (0.36) | ENPP2METCTSVCTSLCTSS | |
| SCHEMBL13275160 | 0.83 | FYN (0.34) | ENPP2METCTSVCTSLCTSS | |
| SCHEMBL2269058 | 0.83 | ENPP2 (0.41) | ENPP2METCTSVCTSLCTSS | |
| SCHEMBL2264266 | 0.82 | HSD17B13 (0.37) | ENPP2METHSD17B13IRAK4IRAK1 | |
| SCHEMBL13275650 | 0.82 | ENPP2 (0.35) | ENPP2METCTSVCTSLCTSS | |
| SCHEMBL2273583 | 0.81 | ENPP2 (0.33) | ENPP2METCTSVCTSLCTSS | |
| SCHEMBL2219418 | 0.81 | IRAK1 (0.36) | ENPP2METCTSVCTSLCTSS | |
| SCHEMBL2271291 | 0.81 | HSD17B13 (0.38) | ENPP2METHSD17B13IRAK4IRAK1 | |
| SCHEMBL2261414 | 0.81 | HSD17B13 (0.42) | ENPP2METHSD17B13IRAK4IRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084402-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |