Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | GCG | P01275 | 4/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480770 | 1.00 | EGLN1 (0.42) | EGLN1GRM4METMST1RGCG | |
| SCHEMBL22736533 | 0.86 | EGLN1 (0.38) | EGLN1GRM4METMST1RGCG | |
| SCHEMBL29480668 | 0.86 | EGLN1 (0.38) | EGLN1GRM4METMST1RGCG | |
| SCHEMBL29567290 | 0.84 | EGLN1 (0.38) | EGLN1GRM4GCGLDHALDHB | |
| SCHEMBL22735741 | 0.81 | EGLN1 (0.39) | EGLN1GRM4METMST1RGCG | |
| SCHEMBL29480703 | 0.81 | EGLN1 (0.39) | EGLN1GRM4METMST1RGCG | |
| SCHEMBL29480747 | 0.77 | GRM4 (0.37) | EGLN1GRM4 | |
| SCHEMBL29589289 | 0.76 | EGLN1 (0.46) | EGLN1 | |
| Hydrochloric Acid SCHEMBL29629385 | 0.75 | EGLN1 (0.45) | EGLN1 | |
| SCHEMBL22736041 | 0.75 | GRM4 (0.32) | EGLN1GRM4GCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |