Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 2/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480668 | 1.00 | EGLN1 (0.38) | EGLN1METMST1RGRM4GCG | |
| SCHEMBL29480770 | 0.86 | EGLN1 (0.42) | EGLN1METMST1RGRM4GCG | |
| SCHEMBL22736535 | 0.86 | EGLN1 (0.42) | EGLN1METMST1RGRM4GCG | |
| SCHEMBL29480652 | 0.86 | EGLN1 (0.34) | EGLN1GRM4 | |
| SCHEMBL22735954 | 0.86 | EGLN1 (0.34) | EGLN1GRM4 | |
| SCHEMBL22735769 | 0.84 | EGLN1 (0.33) | EGLN1GRM4 | |
| SCHEMBL29480690 | 0.84 | OGA (0.34) | EGLN1GRM4 | |
| SCHEMBL29480744 | 0.81 | LMNA (0.44) | EGLN1GRM4 | |
| SCHEMBL22735928 | 0.81 | GRM4 (0.33) | EGLN1GRM4 | |
| SCHEMBL29480752 | 0.81 | GRM4 (0.33) | EGLN1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |