Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | GCG | P01275 | 2/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22735954 | 0.86 | EGLN1 (0.34) | EGLN1GRM4MELK | |
| SCHEMBL29480652 | 0.86 | EGLN1 (0.34) | EGLN1GRM4MELK | |
| SCHEMBL29480770 | 0.84 | EGLN1 (0.42) | EGLN1GRM4GCGLDHALDHB | |
| SCHEMBL22736535 | 0.84 | EGLN1 (0.42) | EGLN1GRM4GCGLDHALDHB | |
| SCHEMBL22736041 | 0.81 | GRM4 (0.32) | EGLN1GRM4GCG | |
| SCHEMBL22736320 | 0.81 | GRM4 (0.32) | EGLN1GRM4GCG | |
| SCHEMBL29567465 | 0.81 | GRM4 (0.32) | EGLN1GRM4GCG | |
| SCHEMBL29567639 | 0.81 | GRM4 (0.32) | EGLN1GRM4GCG | |
| SCHEMBL29480647 | 0.79 | MELK (0.51) | EGLN1MELKGCG | |
| SCHEMBL22736230 | 0.79 | GRM4 (0.38) | EGLN1GRM4GCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976612-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD (IN) | 2022-04-06 | — | — | EP | disclosed |