Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21168975 | 0.87 | MEN1 (0.41) | MEN1KMT2ARAB9AASIC3COMT | |
| SCHEMBL26033261 | 0.81 | CYP19A1 (0.41) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL15871198 | 0.81 | MEN1 (0.43) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL23181340 | 0.81 | AGTR1 (0.41) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL20125555 | 0.81 | AGTR1 (0.41) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL23033831 | 0.79 | MAPT (0.44) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL17033540 | 0.78 | MEN1 (0.61) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL23682198 | 0.78 | KMT2A (0.46) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL19447578 | 0.77 | CCR1 (0.52) | ADORA2ATDP1HTR1ADRD2ADORA1 | |
| SCHEMBL3807753 | 0.77 | ALDH1A1 (0.36) | RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055303-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-02 | — | — | EP | disclosed |