SCHEMBL22736766

SCHEMBL22736766

c1ccc(-c2ccc3nc(-c4ccc5sc6c(-c7ccc(-c8nc(-c9ccccc9)nc(-c9ccc%10c(c9)sc9ccccc9%10)n8)cc7)cccc6c5c4)oc3c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VSIR Q9H7M9 7/20 0.41
PRKDC P78527 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPT P10636 5/20 0.37
KDM4E B2RXH2 4/20 0.37
NPC1 O15118 4/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 4/20 0.37
RAB9A P51151 4/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
GAA P10253 2/20 0.37
NFKB1 P19838 2/20 0.37
NFKB2 Q00653 2/20 0.37
RELA Q04206 2/20 0.37
TP53 P04637 2/20 0.37
LMNA P02545 1/20 0.37
STAT1 P42224 1/20 0.37
GFER P55789 1/20 0.37
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22736761 0.97 VSIR (0.43) VSIRPRKDCALOX5MAPTKDM4E
SCHEMBL22736421 0.93 NPC1 (0.39) PRKDCALOX5MAPTKDM4ENPC1
SCHEMBL22736555 0.93 KDM4E (0.43) PRKDCALOX5MAPTKDM4ENPC1
SCHEMBL22736080 0.92 VSIR (0.42) VSIRPRKDCALOX5MAPTKDM4E
SCHEMBL22736420 0.90 ALOX5 (0.39) PRKDCALOX5MAPTKDM4ENPC1
SCHEMBL22736764 0.90 VSIR (0.40) VSIRPRKDCALOX5MAPTKDM4E
SCHEMBL22736553 0.90 KDM4E (0.42) PRKDCALOX5MAPTKDM4ENPC1
SCHEMBL22736058 0.89 NPC1 (0.39) PRKDCALOX5MAPTKDM4ENPC1
SCHEMBL22736765 0.89 VSIR (0.39) VSIRPRKDCALOX5MAPTKDM4E
SCHEMBL23473651 0.89 ALOX5 (0.40) VSIRPRKDCALOX5MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020242161-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-12-03 WO disclosed