SCHEMBL22736767

SCHEMBL22736767

c1ccc(-c2ccc3nc(-c4ccc5sc6c(-c7cccc(-c8nc(-c9ccccc9)nc(-c9ccc%10oc%11ccccc%11c%10c9)n8)c7)cccc6c5c4)oc3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VSIR Q9H7M9 6/20 0.39
KDM4E B2RXH2 3/20 0.37
NPC1 O15118 3/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
TP53 P04637 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
NFKB1 P19838 1/20 0.37
STAT1 P42224 1/20 0.37
GFER P55789 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
ALOX5 P09917 1/20 0.35
HPSE Q9Y251 2/20 0.35
HCRTR1 O43613 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22736765 0.96 VSIR (0.39) VSIRKDM4ENPC1ALDH1A1MAPT
SCHEMBL22736415 0.94 NPC1 (0.39) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22736557 0.94 KDM4E (0.41) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22736445 0.92 KDM4E (0.40) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22736399 0.91 NPC1 (0.38) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22736626 0.91 KDM4E (0.41) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22736562 0.91 KDM4E (0.41) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22701874 0.91 ALOX5 (0.42) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22701825 0.91 ALOX5 (0.42) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL22736763 0.90 VSIR (0.40) VSIRKDM4ENPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020242161-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-12-03 WO disclosed