SCHEMBL22736772

SCHEMBL22736772

B[C@@H]1O[C@H](COP(=O)(S)OC2C(OC)[C@H](B)O[C@@H]2CO)C(O)C1OC

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 1/20 0.37
▸ LGALS8 O00214 2/20 0.36
▸ IGF2R P11717 4/20 0.32
▸ AMDHD2 Q9Y303 1/20 0.32
▸ LGALS3 P17931 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20334736 0.88 — —
SCHEMBL23984435 0.86 FBP1 (0.34) FBP1LGALS8IGF2R
SCHEMBL14592737 0.82 FBP1 (0.44) FBP1IGF2RAMDHD2
SCHEMBL26474225 0.81 — —
SCHEMBL24211093 0.81 — —
SCHEMBL20329196 0.81 — —
SCHEMBL15293066 0.80 FBP1 (0.59) FBP1IGF2RAMDHD2
SCHEMBL14928402 0.80 FBP1 (0.59) FBP1IGF2RAMDHD2
SCHEMBL18844825 0.80 FBP1 (0.59) FBP1IGF2RAMDHD2
SCHEMBL17789075 0.80 FBP1 (0.59) FBP1IGF2RAMDHD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200377886-A1 EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY SAREPTA THERAPEUTICS, INC. (US) 2020-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377886-A1 EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY UTRN, SMN1; SMN2, RBM17 FBP1 3177/4885LGALS8 2367/4885IGF2R 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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