Sugi Predict

Sugi Predict / Compounds / SCHEMBL22737403

SCHEMBL22737403

SCHEMBL22737403

N#Cc1cccc(C#N)c1-c1ccc2c(c1)c1ccccc1n2-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ ATM Q13315 1/20 0.51
▸ KMT2A Q03164 3/20 0.38
▸ IMPDH2 P12268 1/20 0.36
▸ PTGER4 P35408 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.35
▸ SMN1; SMN2 Q16637 4/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ MAOA P21397 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ IL1R1 P14778 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ HDAC4 P56524 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22737285 0.96 KDM4E (0.47) L3MBTL1KDM4EATMKMT2AIMPDH2
SCHEMBL22737221 0.96 KDM4E (0.47) L3MBTL1KDM4EATMKMT2AIMPDH2
SCHEMBL22737005 0.96 KDM4E (0.44) L3MBTL1KDM4EATMKMT2AIMPDH2
SCHEMBL22737104 0.96 KDM4E (0.43) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL22737183 0.94 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AIMPDH2
SCHEMBL22737296 0.94 KDM4E (0.43) L3MBTL1KDM4EATMKMT2AIMPDH2
SCHEMBL22737097 0.94 KDM4E (0.43) L3MBTL1KDM4EATMKMT2AIMPDH2
SCHEMBL22737006 0.94 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AIMPDH2
SCHEMBL22737500 0.93 KDM4E (0.42) L3MBTL1KDM4EATMALDH1A1SMN1; SMN2
SCHEMBL22737449 0.93 KDM4E (0.50) L3MBTL1KDM4EATMKMT2AIMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914378-A Composition for use in organic light emitting diodes 九州有机光材股份有限公司 2020-03-24 — — CN claimed
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 — — US disclosed
US-20200377490-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME, AND ELECTRONIC DEVICE INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-12-03 — — US disclosed
CN-110914378-A Composition for use in organic light emitting diodes 九州有机光材股份有限公司 2020-03-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 L3MBTL1 2377/4885KDM4E 3163/4885ATM 953/4885
US-20200377490-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME, AND ELECTRONIC DEVICE INCLUDING ORGANIC LIGHT-EMITTING DEVICE CCNE2, CRY2, PER2 L3MBTL1 2024/4885KDM4E 3559/4885ATM 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.