SCHEMBL2273886

SCHEMBL2273886

CC(C)(C)OC(=O)N1CC1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.42
NR1H2 P55055 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
USP2 O75604 1/20 0.39
HTRA1 Q92743 1/20 0.38
HPGD P15428 1/20 0.37
BTK Q06187 1/20 0.37
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25929622 1.00 HSD17B10 (0.48) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL7531758 0.87 NR1H3 (0.41) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL21924897 0.84 NAMPT (0.43) NR1H2CYP1A2POLBCYP3A4CYP2C19
SCHEMBL3442335 0.84 HSD17B10 (0.43) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL1315955 0.84 HSD17B10 (0.43) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL24645252 0.84 HSD17B10 (0.43) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL8214873 0.84 HSD17B10 (0.43) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL5200883 0.84 ATM (0.59) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL17033098 0.84 HSD17B10 (0.43) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1
SCHEMBL116439 0.84 ATM (0.59) HSD17B10SMN1; SMN2NR1H2CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025058459-A1 NOVEL IMIDAZOPYRIDINE-BASED COMPOUND AND COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING, ALLEVIATING, OR TREATING GASTROINTESTINAL INFLAMMATORY DISEASES OR GASTRIC ACID-RELATED DISEASES (주)휴온스 2025-03-20 WO disclosed
US-7989634-B2 Melanocortin receptor agonists LG LIFE SCIENCES LTD. (KR) 2011-08-02 US disclosed
US-20090221546-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE PFIZER INC 2009-09-03 US disclosed
US-20080287674-A1 Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade WARNER-LAMBERT COMPANY LLC 2008-11-20 US disclosed
EP-1685102-A4 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD (KR) 2008-08-20 EP disclosed
US-7407974-B2 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade PFIZER INC. (US) 2008-08-05 US disclosed
US-7407972-B2 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade PFIZER INC. (US) 2008-08-05 US disclosed
US-20070129346-A1 Melanocortin receptor agonists LG LIFE SCIENCES LTD. (KR) 2007-06-07 US disclosed
EP-1685102-A1 MELANOCORTIN RECEPTOR AGONISTS LG Life Sciences Ltd. (KR) 2006-08-02 EP disclosed
US-20050250815-A1 Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade WARNER-LAMBERT COMPANY LLC 2005-11-10 US disclosed
WO-2005047253-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2005-05-26 WO disclosed
WO-2005047251-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2005-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287674-A1 Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade TFPI, F11, F2 HSD17B10 1622/4885SMN1; SMN2 3201/4885NR1H2 2853/4885
US-20090221546-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE F11, F2, TFPI HSD17B10 1489/4885SMN1; SMN2 2983/4885NR1H2 2778/4885
US-20070129346-A1 Melanocortin receptor agonists MC1R, MC3R, MC5R HSD17B10 1389/4885SMN1; SMN2 2404/4885NR1H2 556/4885
US-20050250815-A1 Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade F12, TFPI, F11 HSD17B10 2542/4885SMN1; SMN2 2097/4885NR1H2 2709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.