SCHEMBL2273902

SCHEMBL2273902

CC[SiH](CCl)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
LMNA P02545 1/20 0.33
PSIP1 O75475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80927 0.85 TP53 (0.41) TP53LMNAPSIP1
SCHEMBL27427909 0.85 TSHR (0.35)
Fluoride SCHEMBL27660896 0.82 TP53 (0.39) TP53LMNAPSIP1
Water SCHEMBL20720558 0.82 TP53 (0.39) TP53LMNAPSIP1
SCHEMBL10318638 0.82 TP53 (0.32) TP53LMNA
SCHEMBL12816111 0.79 LTA4H (0.33)
SCHEMBL12814850 0.77 TAAR1 (0.33) TP53LMNA
SCHEMBL10317670 0.77 NPC1 (0.35) TP53
SCHEMBL27694214 0.76 TAAR1 (0.37)
SCHEMBL27669962 0.76 TAAR1 (0.38) TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62099386-A None JP disclosed
CN-104471387-B Fixing phase 株式会社大赛璐 2016-08-24 CN disclosed
CN-104471387-A Stationary phase DAICEL CORP 2015-03-25 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-5514734-A Polymer nanocomposites comprising a polymer and an exfoliated particulate material derivatized with organo silanes, organo titanates, and organo zirconates dispersed therein and process of preparing same ALLIEDSIGNAL INC. (US) 1996-05-07 US disclosed
WO-1995006090-A1 POLYMER NANOCOMPOSITES COMPRISING A POLYMER AND AN EXFOLIATED PARTICULATE MATERIAL DERIVATIZED WITH ORGANO SILANES, ORGANO TITANATES AND ORGANO ZIRCONATES DISPERSED THEREIN AND PROCESS OF PREPARING SAME ALLIEDSIGNAL INC. (US) 1995-03-02 WO disclosed
US-5385776-A Polylactams ALLIEDSIGNAL INC. 1995-01-31 US disclosed
JP-S6299386-A ETHYLMETHYLPHENYLSILYLACETIC ACID AND DETERMINATION OF OPTICAL PURITY THEREWITH NOHIRA HIROYUKI 1987-05-08 JP disclosed