SCHEMBL80927

SCHEMBL80927

CC[SiH](CC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
LMNA P02545 2/20 0.39
PSIP1 O75475 1/20 0.35
TAAR1 Q96RJ0 4/20 0.33
SLC6A2 P23975 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
HIF1A Q16665 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL20720558 0.97 TP53 (0.39) TP53LMNAPSIP1TAAR1SLC6A2
Fluoride SCHEMBL27660896 0.97 TP53 (0.39) TP53LMNAPSIP1TAAR1SLC6A2
SCHEMBL29847552 0.85 TP53 (0.35) TP53LMNAPSIP1SIGMAR1CES2
SCHEMBL27669962 0.85 TAAR1 (0.38) TP53LMNATAAR1SLC6A2SIGMAR1
SCHEMBL2273902 0.85 TP53 (0.35) TP53LMNAPSIP1
SCHEMBL706778 0.84
SCHEMBL16395648 0.83 TAAR1 (0.33) TP53LMNATAAR1SLC6A2SIGMAR1
SCHEMBL10020512 0.83 TP53 (0.33) TP53LMNA
Water SCHEMBL20578142 0.81
SCHEMBL2273783 0.81 HTR2A (0.38) TP53LMNATAAR1SIGMAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220349049-A1 COMPOSITIONS AND METHODS USING SAME FOR DEPOSITION OF SILICON-CONTAINING FILM VERSUM MATERIALS US, LLC (US) 2022-11-03 US claimed
EP-3998304-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SmartKem Limited (GB) 2022-05-18 EP claimed
EP-3977508-A1 COMPOSITIONS AND METHODS USING SAME FOR DEPOSITION OF SILICON-CONTAINING FILM Versum Materials US, LLC (US) 2022-04-06 EP claimed
CN-114174553-A Composition and method for depositing silicon-containing films using the same 弗萨姆材料美国有限责任公司 2022-03-11 CN claimed
CN-113683716-A Ethylene polymerization catalyst, preparation method thereof and preparation method of ethylene-isobutylene copolymer 中国石油天然气股份有限公司 2021-11-23 CN claimed
EP-2817355-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-03-24 EP claimed
EP-2817356-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-02-17 EP claimed
EP-2817354-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-01-13 EP claimed
US-10833274-B2 Organic semiconductor compositions SMARTKEM LIMITED (GB) 2020-11-10 US claimed
EP-2817357-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-11-04 EP claimed
EP-1971664-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG Chem, Ltd. (KR) 2008-09-24 EP claimed
WO-2007081179-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM. LTD. (KR) 2007-07-19 WO claimed
US-20070161803-A1 Method of asymmetrically reducing 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- dimethylbenzoic acid or ester thereof MITSUBISHI PHARMA CORPORATION (JP) 2007-07-12 US claimed
US-20070037012-A1 having an anthracene compound substituted with at least one thiophenyl ring; OLED organic light emitters; as displays with low power consumption, faster response time, higher brightness level, unlimited viewing angle LG CHEM, LTD. (KR) 2007-02-15 US claimed
EP-1719764-A1 METHOD OF ASYMMETRICALLY REDUCING 4- 5-(IMIDAZOL-1-YL)-2-MET HYLBENZOYL -3,5-DIMETHYL-BENZOIC ACID OR ESTER THEREOF Mitsubishi Pharma Corporation (JP) 2006-11-08 EP claimed
EP-1501821-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG Chem, Ltd. (KR) 2005-02-02 EP claimed
US-20040067387-A1 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM. LTD. (KR) 2004-04-08 US claimed
WO-2003095445-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG CHEM, LTD. (KR) 2003-11-20 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161803-A1 Method of asymmetrically reducing 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- dimethylbenzoic acid or ester thereof DDC, AADAC, ALG3 TP53 4626/4885LMNA 4180/4885PSIP1 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.