Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | BAX | Q07812 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1217901 | 0.85 | LTA4H (0.45) | LTA4HTSHRCA5ACA5BCA4 | |
| Fluoride SCHEMBL27845931 | 0.82 | LTA4H (0.43) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL896125 | 0.79 | LTA4H (0.45) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL4813685 | 0.77 | LTA4H (0.43) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL28193743 | 0.76 | CA4 (0.46) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL27845667 | 0.75 | LTA4H (0.41) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL230789 | 0.74 | LTA4H (0.45) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL28053677 | 0.73 | CA4 (0.42) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL4807486 | 0.72 | LTA4H (0.43) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL4809947 | 0.72 | LTA4H (0.43) | LTA4HTSHRCA5ACA5BCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180324-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH Zürich (CH) | 2017-06-21 | — | — | EP | claimed |
| WO-2016019475-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2016-02-11 | — | — | WO | claimed |
| US-8791100-B2 | Aryl benzylamine compounds | NOVARTIS AG (CH) | 2014-07-29 | — | — | US | disclosed |
| US-20110190258-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190258-A1 | ARYL BENZYLAMINE COMPOUNDS | UGT2B7, NAT1, CYP2B6 | LTA4H 1337/4885TSHR 1964/4885CA5A 3082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.