SCHEMBL2274161

SCHEMBL2274161

CCCCCCC(C)Cc1ccc(C(=O)O)c(C(=O)O)c1CC(C)CCCCCC

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
ACE2 Q9BYF1 1/20 0.41
PPARA Q07869 4/20 0.38
BID P55957 3/20 0.38
MCL1 Q07820 3/20 0.38
KAT8 Q9H7Z6 3/20 0.38
BCL2L1 Q07817 2/20 0.38
BAK1 Q16611 2/20 0.38
PPARG P37231 2/20 0.38
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT5 Q92993 1/20 0.38
SAE1 Q9UBE0 1/20 0.38
RARB P10826 2/20 0.38
RARA P10276 1/20 0.38
RARG P13631 1/20 0.38
SLC37A4 O43826 1/20 0.36
GPR84 Q9NQS5 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446637 0.99 ALDH1A1 (0.41) ALDH1A1ACE2PPARABIDMCL1
SCHEMBL1447654 0.95 ALDH1A1 (0.36) ALDH1A1ACE2PPARABIDMCL1
SCHEMBL1446880 0.89 PLA2G1B (0.33) ALDH1A1PPARABIDMCL1KAT8
SCHEMBL9649914 0.84 PPARA (0.41) ALDH1A1PPARABIDMCL1KAT8
SCHEMBL1446930 0.83 MAPT (0.36) ALDH1A1
SCHEMBL4072756 0.83 PRSS1 (0.43) ALDH1A1PPARABIDMCL1KAT8
SCHEMBL6444607 0.83 ALDH1A1 (0.48) ALDH1A1ACE2PPARAKAT8PPARG
SCHEMBL4215205 0.83 ALDH1A1 (0.31) ALDH1A1PPARABIDMCL1KAT8
SCHEMBL11557462 0.82 PRSS1 (0.41) ALDH1A1PPARABIDMCL1KAT8
SCHEMBL541935 0.82 PPARA (0.38) ALDH1A1PPARABIDMCL1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196103-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST MITSUI CHEMICALS, INC. (US) 2011-08-11 US disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
US-20090043050-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2009-02-12 US disclosed
US-7488789-B2 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-02-10 US disclosed
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-18 US disclosed
US-20080306234-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080306219-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080292896-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-11-27 US disclosed
US-20060276607-A1 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2006-12-07 US disclosed
US-6753378-B2 GRAFTED WITH CARBOXYL- OR ANHYDRIDE CONTAINING COMPOUND; MELT PROCESSABILITY, CHEMICAL RESISTANCE, ELECTRICAL AND MECHANICAL PROPERTIES; INJECTION AND BLOW MOLDING; FILMS, SHEETS MITSUI CHEMICALS, INC. (JP) 2004-06-22 US disclosed
US-20030023002-A1 Branched polyolefin, process for producing the same, and thremoplastic resin composition containing branched polyolefin MITSUI CHEMICALS, INC. (JP) 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST PPIA, PPOX, PTGES2 ALDH1A1 3243/4885ACE2 1393/4885PPARA 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.