SCHEMBL2274193

SCHEMBL2274193

CCCCN(CC)[SiH2]CC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA9 Q16790 3/20 0.34
CA2 P00918 1/20 0.32
DNM1 Q05193 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ALDH2 P05091 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271164 0.87 CA12 (0.33) CA12CA1CA9CA2DNM1
SCHEMBL2102495 0.81 CA12 (0.34) CA12CA1CA9
SCHEMBL16582983 0.78 CA12 (0.37) CA12CA1CA9CA2DNM1
SCHEMBL2268201 0.76
SCHEMBL27966977 0.76
SCHEMBL2100519 0.75 TSHR (0.36) TSHR
SCHEMBL2272475 0.72 TSHR (0.33) LMNATSHR
SCHEMBL15606108 0.72 CA12 (0.33) CA12CA1CA9CA2
SCHEMBL2549420 0.71 CA12 (0.40) CA12CA1CA9CA2DNM1
SCHEMBL2269630 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102159596-B Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO LTD 2014-05-07 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed