SCHEMBL2274207

SCHEMBL2274207

CCCCC(=C[SiH2]NC)CCCC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.33
CES2 O00748 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270107 0.86
SCHEMBL2272482 0.80 ALDH1A1 (0.32) CES1CES2ALDH1A1TP53
SCHEMBL15303920 0.76 CES1 (0.36) CES1CES2ALDH1A1TP53CA1
SCHEMBL3482411 0.73 CES1 (0.38) CES1CES2ALDH1A1TP53CA1
SCHEMBL15303885 0.71 CES1 (0.36) CES1CES2ALDH1A1TP53CA1
SCHEMBL2273375 0.71 ALDH1A1 (0.44) CES1CES2ALDH1A1TP53CA1
SCHEMBL15303917 0.68 CES1 (0.33) CES1CES2ALDH1A1TP53CA1
SCHEMBL704775 0.68 ALDH1A1 (0.38) CES1CES2ALDH1A1TP53CA1
SCHEMBL705617 0.67 ALDH1A1 (0.32) CES1CES2ALDH1A1TP53
SCHEMBL8968327 0.66 CES1 (0.45) CES1CES2ALDH1A1TP53CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed