Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11977441 | 0.77 | LMNA (0.47) | LMNAKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL22744240 | 0.77 | MAPT (0.43) | LMNAKDM4ECYP3A4MAPTTSHR | |
| SCHEMBL22744401 | 0.77 | SSTR4 (0.53) | LMNAKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL22743887 | 0.75 | KDM4E (0.46) | LMNAKDM4EMAPTTSHRTDP1 | |
| Phenanthroline SCHEMBL27830964 | 0.73 | LMNA (0.59) | LMNAKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL22744388 | 0.71 | MAPK13 (0.35) | LMNAALDH1A1RAB9A | |
| SCHEMBL9933113 | 0.71 | KEAP1 (0.41) | LMNAHTTSMN1; SMN2SSTR4HTR2C | |
| SCHEMBL4152822 | 0.71 | LMNA (0.52) | LMNAKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL4307834 | 0.71 | MAPT (0.52) | LMNAKDM4ECYP3A4CYP2D6MAPT | |
| SCHEMBL24650488 | 0.70 | KDM4E (0.37) | LMNAKDM4ECYP3A4CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020241853-A1 | BENZOTRIAZOLE DERIVATIVE | 宇部興産株式会社 | 2020-12-03 | — | — | WO | disclosed |