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SCHEMBL22745255

SCHEMBL22745255

Cc1ccc2c(c1)C(Cc1ccc(C(=O)C(C)(C)N3CCSCC3)cc1)(Cc1ccc(C(=O)C(C)(C)N3CCSCC3)cc1)c1cc(C(=O)C(C)(C)N3CCSCC3)ccc1-2

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ HTT P42858 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HDAC1 Q13547 1/20 0.30
▸ HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22745441 0.94 SMN1; SMN2 (0.36) HPGDALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL22745182 0.89 PDK2 (0.34) ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL22745173 0.87 ALDH1A1 (0.48) HPGDALDH1A1SMN1; SMN2HTTTSHR
SCHEMBL22745416 0.84 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL22745177 0.83 PDK2 (0.43) HPGDALDH1A1SMN1; SMN2TSHR
SCHEMBL22745169 0.81 ALDH1A1 (0.53) HPGDALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL22745180 0.77 ALDH1A1 (0.49) HPGDALDH1A1SMN1; SMN2HTTTSHR
SCHEMBL22745167 0.77 TSHR (0.48) HPGDALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL22745258 0.76 CA2 (0.33) HPGD
SCHEMBL22745171 0.74 PDK2 (0.35) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020238862-A1 FLUORENE INITIATOR, PHOTOCURABLE COMPOSITION COMPRISING SAME, AND APPLICATION THEREOF 常州强力先端电子材料有限公司 2020-12-03 — — WO disclosed
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