SCHEMBL2274749

SCHEMBL2274749

CCCC[SiH2]CCCC(N(C)C)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.32
TSHR P16473 1/20 0.30
THRB P10828 1/20 0.30
FDPS P14324 3/20 0.30
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2266558 0.91 DNM1 (0.31) DNM1
SCHEMBL2271021 0.84
SCHEMBL2270202 0.80 PLA2G1B (0.35) DNM1
SCHEMBL1993400 0.80 DNM1 (0.48) DNM1TSHRTHRBFDPS
SCHEMBL2270019 0.78
SCHEMBL8746175 0.78 TSHR (0.47) DNM1TSHRTHRBFDPS
SCHEMBL9166797 0.78 TSHR (0.47) DNM1TSHRTHRBFDPS
SCHEMBL125535 0.78 TSHR (0.47) DNM1TSHRTHRBFDPS
SCHEMBL8824514 0.78 TSHR (0.47) DNM1TSHRTHRBFDPS
SCHEMBL6049165 0.78 TSHR (0.47) DNM1TSHRTHRBFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed