SCHEMBL22747699

SCHEMBL22747699

c1ccc2c(c1)-c1ccc(-n3c4ccccc4c4ccccc43)cc1C21c2ccccc2-c2c1ccc1c2oc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PGR P06401 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15989852 0.93 KDM4E (0.34) ALOX5KDM4EATML3MBTL1
SCHEMBL24676045 0.88 ALOX5 (0.36) ALOX5KDM4EATML3MBTL1
SCHEMBL18086179 0.87 ALOX5 (0.36) ALOX5
SCHEMBL18086181 0.87 ALOX5 (0.36) ALOX5
SCHEMBL17879462 0.86 ALOX5 (0.36) ALOX5PGRKDM4EATML3MBTL1
SCHEMBL18086186 0.86 ALOX5 (0.36) ALOX5
SCHEMBL18086190 0.86 ALOX5 (0.36) ALOX5
SCHEMBL24936767 0.85 ALOX5 (0.47) ALOX5KDM4EATML3MBTL1
SCHEMBL16744758 0.84 PGR (0.38) ALOX5PGRKDM4EATML3MBTL1
SCHEMBL16855317 0.84 ESR1 (0.40) PGRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11424418-B2 Metal complex organic electroluminescent material and organic electroluminescent device SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2022-08-23 US disclosed
US-20200381633-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-12-03 US disclosed