SCHEMBL22747729

SCHEMBL22747729

CN(C(=O)O)C1CC2(CC(O)C2)C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.34
APLNR P35414 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21997532 0.82 ESR1 (0.35)
SCHEMBL15751664 0.76 ALOX15 (0.31) APLNR
SCHEMBL17044867 0.75 CYP2C19 (0.31) CYP2C19
SCHEMBL31020426 0.74 ASGR1 (0.39)
SCHEMBL3829058 0.73
SCHEMBL3829062 0.73
SCHEMBL3831930 0.73
SCHEMBL481634 0.71 ALDH1A1 (0.35)
SCHEMBL20973330 0.71 ALDH1A1 (0.35)
SCHEMBL1498386 0.71 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020244452-A1 HETEROCYCLIC DERIVATIVE HAVING β2 RECEPTOR AGITATION AND M RECEPTOR ANTAGONISTIC ACTIVITY AND MEDICAL USE THEREOF 中国医药研究开发中心有限公司 2020-12-10 WO disclosed