Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395773 | 0.84 | S1PR1 (0.33) | KMT2AAGBL2 | |
| SCHEMBL19706324 | 0.84 | HCAR2 (0.44) | HCAR2P4HA1P4HTMMIFKDM4E | |
| SCHEMBL22924509 | 0.79 | HPGDS (0.49) | GABRA5 | |
| SCHEMBL25047559 | 0.79 | HCAR2 (0.43) | HCAR2P4HA1P4HTMMIFKDM4E | |
| SCHEMBL1608329 | 0.76 | HCAR2 (0.47) | HCAR2P4HA1P4HTMMIFKDM4E | |
| SCHEMBL846024 | 0.75 | HCAR2 (0.50) | HCAR2P4HA1P4HTMMIFKDM4E | |
| SCHEMBL15350036 | 0.73 | HCAR2 (0.48) | HCAR2P4HA1P4HTMMIFKDM4E | |
| SCHEMBL31681508 | 0.73 | HCAR2 (0.48) | HCAR2P4HA1P4HTMMIFKDM4E | |
| SCHEMBL2601852 | 0.73 | HCAR2 (0.48) | HCAR2P4HA1P4HTMMIFKDM4E | |
| SCHEMBL9504528 | 0.73 | HCAR2 (0.48) | HCAR2P4HA1P4HTMMIFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244970-A1 | NEW CARBOCYCLIC PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2020-12-10 | — | — | WO | disclosed |