Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.48 |
| ▸ | LPL | P06858 | 7/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18025836 | 0.82 | LIPG (0.55) | LIPGLPLALOX5MEN1TP53 | |
| SCHEMBL12234041 | 0.82 | LIPG (0.55) | LIPGLPLALOX5MEN1TP53 | |
| SCHEMBL1336781 | 0.82 | LIPG (0.55) | LIPGLPLALOX5MEN1TP53 | |
| SCHEMBL17525546 | 0.80 | ROCK1 (0.38) | LIPGLPLROCK1 | |
| SCHEMBL22748822 | 0.79 | LPL (0.61) | LIPGLPLTP53CYP3A4SPHK2 | |
| SCHEMBL22748247 | 0.79 | LPL (0.61) | LIPGLPLTP53CYP3A4PTGS2 | |
| SCHEMBL22748365 | 0.78 | LIPG (0.52) | LIPGLPLALOX5ROCK1MEN1 | |
| SCHEMBL22748290 | 0.78 | LPL (0.40) | LIPGLPLROCK1 | |
| SCHEMBL1646761 | 0.78 | LPL (0.44) | LIPGLPLROCK1 | |
| SCHEMBL17165827 | 0.77 | ROCK1 (0.36) | LIPGLPLROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |