Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.41 |
| ▸ | HMGCR | P04035 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748644 | 0.85 | FFAR1 (0.41) | FFAR1FFAR4MMP2MMP12CYSLTR2 | |
| SCHEMBL21061152 | 0.74 | BID (0.43) | MMP2KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL21060899 | 0.74 | BID (0.43) | MMP2KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL21060983 | 0.74 | BID (0.43) | MMP2KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL21060976 | 0.74 | BID (0.43) | MMP2KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL21061161 | 0.74 | BID (0.43) | MMP2KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL21060891 | 0.74 | BID (0.43) | MMP2KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL23645985 | 0.71 | PLA2G2A (0.44) | TDP1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL23645975 | 0.71 | PLA2G2A (0.44) | TDP1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL21060959 | 0.71 | GABRA1 (0.41) | FFAR1FFAR4GPR84TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | claimed |
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |