Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 7/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748606 | 1.00 | PLA2G4A (0.47) | PLA2G4ATP53TSHRRARBPLA2G4B | |
| SCHEMBL22748568 | 1.00 | PLA2G4A (0.47) | PLA2G4ATP53TSHRRARBPLA2G4B | |
| SCHEMBL22748990 | 1.00 | PLA2G4A (0.47) | PLA2G4ATP53TSHRRARBPLA2G4B | |
| SCHEMBL22748657 | 0.88 | PLA2G4A (0.46) | PLA2G4ATP53TSHRRARBPLA2G4B | |
| SCHEMBL22748674 | 0.88 | PLA2G4A (0.46) | PLA2G4ATP53TSHRRARBPLA2G4B | |
| SCHEMBL22748639 | 0.85 | MGLL (0.40) | PLA2G4ATP53TSHRMAPTCNR1 | |
| SCHEMBL22748736 | 0.85 | MGLL (0.40) | PLA2G4ATP53TSHRMAPTCNR1 | |
| SCHEMBL22748742 | 0.85 | MGLL (0.40) | PLA2G4ATP53TSHRMAPTCNR1 | |
| SCHEMBL22748595 | 0.85 | MGLL (0.40) | PLA2G4ATP53TSHRMAPTCNR1 | |
| SCHEMBL22748567 | 0.85 | PLA2G4A (0.46) | PLA2G4ATP53TSHRRARBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245291-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | claimed |
| WO-2020245291-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |