Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748731 | 0.86 | TLR8 (0.39) | MGLLGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22748745 | 0.85 | PLA2G4A (0.47) | PLA2G4AALDH1A1ACE2CNR1 | |
| SCHEMBL22748687 | 0.81 | CNR1 (0.52) | MGLLGRM2PLA2G4ATLR8ALDH1A1 | |
| SCHEMBL28251168 | 0.81 | CNR1 (0.52) | MGLLGRM2PLA2G4ATLR8ALDH1A1 | |
| SCHEMBL22748579 | 0.79 | MGLL (0.41) | MGLLGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22748681 | 0.75 | CNR1 (0.42) | MGLLGRM2PLA2G4ATLR8ALDH1A1 | |
| SCHEMBL22748736 | 0.74 | MGLL (0.40) | MGLLGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22748639 | 0.74 | MGLL (0.40) | MGLLGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22748712 | 0.74 | CNR1 (0.41) | MGLLGRM2PLA2G4ATLR8CNR1 | |
| SCHEMBL22748595 | 0.74 | MGLL (0.40) | MGLLGRM2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245291-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |