Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 3/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | CLK2 | P49760 | 3/20 | 0.51 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.51 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | ROS1 | P08922 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 2/20 | 0.51 |
| ▸ | MARK3 | P27448 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13218401 | 0.79 | SRC (0.50) | DYRK3RPS6KB1CSNK1A1CSNK1DCLK2 | |
| SCHEMBL130592 | 0.79 | SRC (0.50) | DYRK3RPS6KB1CSNK1A1CSNK1DCLK2 | |
| SCHEMBL23057484 | 0.78 | EGFR (0.42) | RPS6KB1CSNK1A1CSNK1DCLK2DYRK1A | |
| SCHEMBL868744 | 0.75 | PIK3CD (0.51) | DYRK3RPS6KB1CSNK1A1CSNK1DCLK2 | |
| SCHEMBL868687 | 0.75 | ABL1 (0.58) | SRCRETKDREGFRPIK3CG | |
| SCHEMBL15471369 | 0.75 | SRC (0.58) | RPS6KB1CSNK1A1CSNK1DCLK2SLK | |
| SCHEMBL24096480 | 0.74 | JAK2 (0.86) | DYRK3RPS6KB1CSNK1A1CSNK1DCLK2 | |
| SCHEMBL16701523 | 0.74 | ADK (0.49) | DYRK3RPS6KB1CSNK1A1CSNK1DCLK2 | |
| SCHEMBL401337 | 0.73 | SRC (0.45) | DYRK3RPS6KB1CSNK1A1CSNK1DCLK2 | |
| SCHEMBL868521 | 0.73 | DYRK3 (0.51) | DYRK3RPS6KB1CSNK1A1CSNK1DCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980554-A1 | HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES | F. Hoffmann-La Roche AG (CH) | 2022-04-13 | — | — | EP | claimed |
| WO-2020245377-A1 | HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-12-10 | — | — | WO | claimed |
| EP-3138842-B1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON'S TYROSINE KINASE INHIBITORS | ZHEJIANG DTRM BIOPHARMA CO LTD (CN) | 2020-12-09 | — | — | EP | disclosed |