SCHEMBL22749064

SCHEMBL22749064

[CH2]CC(C)(C)CCCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
GGPS1 O95749 6/20 0.38
FDPS P14324 9/20 0.37
FFAR1 O14842 1/20 0.36
CPT2 P23786 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SMPD1 P17405 2/20 0.35
CES2 O00748 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28153722 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL10758322 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL13583489 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL3341692 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL1971804 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL8755240 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL11016467 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL1176711 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL1971557 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1
SCHEMBL27680812 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024018761-A1 NEUTRAL LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
US-20240024252-A1 LIPID NANOPARTICLE NITTO DENKO CORPORATION (JP) 2024-01-25 US disclosed
WO-2024018762-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2023191050-A1 PHARMACEUTICAL COMPOSITION FOR DELIVERY TO CANCER, OR IMMUNOSTIMULATING COMPOSITION 日東電工株式会社 2023-10-05 WO disclosed
WO-2023188830-A1 LIPID NANOPARTICLES 国立大学法人北海道大学 2023-10-05 WO disclosed
EP-4223314-A1 LIPID NANOPARTICLE National University Corporation Hokkaido University (JP) 2023-08-09 EP disclosed
CN-116367718-A Lipid nanoparticles 国立大学法人北海道大学 2023-06-30 CN disclosed
WO-2020245291-A1 PYRROLE DERIVATIVES AS ACC INHIBITORS ALMIRALL, S.A. (ES) 2020-12-10 WO disclosed
CN-100422124-C Fused ring compound DAINIPPON INK & CHEMICALS (JP) 2008-10-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024252-A1 LIPID NANOPARTICLE LIPC, ACOX1, ABCB4 TSHR 985/4885THRB 608/4885GGPS1 2445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.