Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.77 |
| ▸ | PGR | P06401 | 3/20 | 0.77 |
| ▸ | AR | P10275 | 3/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | SHBG | P04278 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | HRH2 | P25021 | 1/20 | 0.77 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.77 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.77 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22761980 | 1.00 | LMNA (0.77) | LMNACYP3A4NR3C1PGRAR | |
| SCHEMBL11511438 | 0.90 | LMNA (0.78) | LMNACYP3A4NR3C1PGRAR | |
| SCHEMBL11511435 | 0.90 | LMNA (0.78) | LMNACYP3A4NR3C1PGRAR | |
| SCHEMBL27048069 | 0.89 | LMNA (0.82) | LMNACYP3A4NR3C1PGRAR | |
| SCHEMBL3973882 | 0.89 | LMNA (0.75) | LMNACYP3A4NR3C1PGRAR | |
| SCHEMBL11511329 | 0.88 | CYP3A4 (0.81) | LMNACYP3A4NR3C1PGRAR | |
| SCHEMBL11511334 | 0.88 | CYP3A4 (0.81) | LMNACYP3A4NR3C1PGRAR | |
| SCHEMBL22749092 | 0.88 | LMNA (0.77) | LMNACYP3A4NR3C1PGRAR | |
| Medroxyprogesterone Acetate SCHEMBL3892232 | 0.87 | NR3C1 (1.00) | LMNACYP3A4NR3C1PGRAR | |
| Medroxyprogesterone Acetate SCHEMBL22761990 | 0.87 | NR3C1 (1.00) | LMNACYP3A4NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025940-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HAFEEZ KALAK ABDUL (IN) | 2024-01-25 | — | — | US | disclosed |
| US-20240025940-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HAFEEZ KALAK ABDUL (IN) | 2024-01-25 | — | — | US | disclosed |
| US-20240025940-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HAFEEZ KALAK ABDUL (IN) | 2024-01-25 | — | — | US | disclosed |
| WO-2020245641-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HAFEEZ KALAK ABDUL (IN) | 2020-12-10 | — | — | WO | disclosed |
| WO-2020245641-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HAFEEZ KALAK ABDUL (IN) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025940-A1 | NOVEL ESTERS OF MEDROXYPROGESTERONE | HSD17B11, CYP19A1, CYP17A1 | LMNA 4253/4885CYP3A4 64/4885NR3C1 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.