Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.57 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.57 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.51 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757451 | 0.86 | ADORA3 (0.41) | ADORA3ADORA1ADORA2ATMIGD3HSP90B1 | |
| SCHEMBL22757475 | 0.85 | ADORA3 (0.40) | ADORA3ADORA1ADORA2ATMIGD3HTR2B | |
| SCHEMBL22750530 | 0.79 | ADORA3 (0.58) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22757494 | 0.79 | ADORA3 (0.58) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22757426 | 0.77 | ADORA3 (0.51) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22757515 | 0.77 | ADORA3 (0.51) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22757320 | 0.74 | ADORA3 (0.44) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22750565 | 0.74 | PGK1 (0.51) | ADORA3ADORA1ADORA2A | |
| SCHEMBL16774370 | 0.73 | ADORA3 (1.00) | ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL16774258 | 0.73 | ADORA3 (1.00) | ADORA3ADORA1ADORA2ATMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |